Lifestyle, medication and socio-demographic determinants of mental and physical health-related quality of life in people with multiple sclerosis
نویسندگان
چکیده
BACKGROUND Health-related quality of life (QOL) is a key outcome for people with multiple sclerosis (MS). While modifiable lifestyle factors, like smoking, physical activity and vitamin D, have strong associations with development and progression of MS, few studies have examined such associations with QOL. METHODS Using patient-reported data from 2312 people with MS from 54 countries, regression models explored associations of socio-demographic, therapeutic and lifestyle factors with QOL, using the Multiple Sclerosis Quality of Life-54 (MSQOL-54). RESULTS Participants were on average 45.6 years old, 82.4% women, mostly partnered (74.1%), with a university degree (59.5%). Controlling for socio-demographic factors and disability, factors associated with better physical health composite (PHC) (on a 100 point scale) were: moderate and high physical activity compared to low (5.9 [95% confidence interval: 4.2, 7.6] and 9.9 [CI: 8.1, 11.6] points higher score respectively); non-smoking compared to current smoking (4.6 points [CI: 2.4, 6.7]); better diet (per 10 points on the 100 point Diet Habits Questionnaire scale (DHQ) 1.6 points [CI: 1.0, 2.2] points); normal body mass index (BMI) versus overweight or obese (2.1 points [CI: 0.4, 3.7] and 2.4 points [CI: 0.5, 4.3]); fewer comorbidities (4.4 points [CI: 3.9, 4.9]); and not taking a disease-modifying drug (DMD) (2.1 points [CI: 0.7, 3.4]). Better mental health composite (MHC) determinants were: moderate and high physical activity compared to low (4.0 points [CI: 2.0, 6.0] and 5.7 points [CI: 3.5, 8.0]); non-smoking compared to current (6.7 points [CI: 4.1, 9.3]); better diet (2.8 points [CI: 1.9, 3.5]); normal BMI versus overweight or obese (3.1 points [CI: 1.1, 5.1] and 3.5 points [CI: 1.3, 5.7]); meditating regularly (2.2 points [CI: 0.2, 4.2]); and no DMD use (2.9 points [CI: 1.3, 4.6]). CONCLUSIONS While causality cannot be concluded from cross-sectional data, the associations between modifiable lifestyle factors and QOL suggest significant potential for secondary prevention of the known deterioration of QOL for people with MS through lifestyle risk factor modification.
منابع مشابه
Quality of Life and its Relative Factors among Patients with Multiple Sclerosis: A Cross-Sectional Study in Northwest Iran
Background: Multiple Sclerosis (MS) is one of the most important diseases due to its adverse clinical, social and economic consequences for affected people. This study tried to assess the quality of life of the patients suffering from Multiple Sclerosis in East Azerbaijan. Methods: This cross-sectional study used the Multiple Sclerosis Quality of Life-54 (MSQOL-54) questionnaire for interviewi...
متن کاملبررسی کیفیت زندگی بیماران عضو انجمن MS شهر یزد
Introduction : Multiple sclerosis (MS) is one of the progressive and chronic disorders of the central nervous system with various symptoms.this symptoms has negative affected on quality of life . this study designed to measure to examine the quality of life in Yazd MS Association. Methods: This was a descriptive and cross-sectional ...
متن کاملEffectiveness of mindfulness integrated cognitive behavioral therapy on the emotional states and quality of life of patients with multiple sclerosis: A clinical trial study
Introduction: The present study was designed to investigate the effectiveness of mindfulness-integrated cognitive behaviour therapy on emotional states (depression, anxiety, & stress) and quality of life (physical health and mental health) of adults with multiple sclerosis. Materials and Methods: The studied population included all patients who referred to Kerman MS society among them 30 patien...
متن کاملEvaluation of Quality of Life and its Related Factors in Elderly in Mashhad in 1396
Objectives As Iran is one of the countries in the world which its population moves toward aging rapidly, it is essential to consider older adults' needs and concerns, which might have an impact on their health-related quality of life. Quality of life is a multi-dimensional concept that has physical, mental, and social components. The present study has been conducted to determine the correlation...
متن کاملSocio-Demographic Determinants of Quality of Life among Older People, a Population-Based Study
Introduction: Social participation is considered one dimension and also determinant of quality of life. The level of social participation of the elderly is influenced by various components such as socio-economic and demographic factors. The present study aimed to assess the relationship between social participation, quality of life, and some socio-economic factors in community dwelling elderly ...
متن کامل